Subarachnoid hemorrhage can reduce the expression of p-Vasp/Vasp in the basilar artery, while a metabotropic glutamate receptor 1 (mGLUR1) negative allosteric modulator can restore the expression of p-Vasp/VASP in the basilar artery after subarachnoid hemorrhage. This evidence concerns the gene GRM1 and subarachnoid hemorrhage.