-Deficiency associated with increased IL-6 production and altered Treg cells peripherally in Alzheimer’s patients (Politis et al., 2010)-B12 deficiency associated with Alzheimer’s, Parkinson’s and vascular dementia, but supplementation only appears to help those with B12 deficiency (Moore et al., 2012). This evidence concerns the gene IL6 and hyperinsulinemic hypoglycemia, familial, 4.