TXNDC12 and central nervous system cancer: In the IDH Mutant subgroups, TCGA (Figure 4B, p < 0.005) and CGGA (Figure 4F, p < 0.005), the expression of TXNDC12 increased significantly with the rise of glioma grade, and the same results were observed in the IDH Wildtype subgroup (Figure 4C, p < 0.005 and Figure 4G, p < 0.005).