Univariate analysis revealed that TXNDC12 is a significant risk factor for glioma in TCGA-RNA-seq (HR = 4.182, 95% CI = 3.185–5.490, p < 0.001) (Figure 2A) and CGGA-RNA-seq (HR = 2.186, 95%CI = 1.943–2.460, p < 0.001) (Figure 2D). The gene discussed is TXNDC12; the disease is glioma.