TP63 and Nail dysplasia: TP63-related disorders have overlapping phenotypic characteristics with various combinations of the following features: ectodermal dysplasia (subjective hypohidrosis, nail dysplasia, sparse hair, skin erosions especially on the scalp associated with areas of scarring and alopecia, hypopigmentation, trismus, excessive freckling, tooth abnormalities), split-hand/foot malformation/syndactyly, lacrimal duct obstruction, hypoplastic breasts and/or nipples, ankyloblepharon filiforme adnatum, hypospadias and cleft lip/palate [1, 2].