Another study that examined the liver lipidome in liver biopsies found that an increase in liver fat and NASH was associated with CER-enriched liver lipidome in patients with “Metabolic NAFLD”, compared to those with “PNPLA3 NAFLD [69].” However, the results of this study did not uncover a strong association between CER and NAFLD. The gene discussed is PNPLA3; the disease is metabolic dysfunction-associated steatotic liver disease.