KIT and systemic mastocytosis: Systemic mastocytosis is a rare mast cell neoplasm of more than one organ driven by the KIT D816V mutation and is divided into different subclassifications [1], of which advanced systemic mastocytosis (AdvSM), indolent systemic mastocytosis (ISM), and smoldering systemic mastocytosis (SSM) are the primary types [2].