ASXL1 and acute myeloid leukemia: The survival study revealed that decreased HGB levels (< 110 g/L), FLT3-ITD mutations, and RUNX1 mutations had a negative influence on the OS of ASXL1+ AML patients (P = 0.045, P = 0.047, and P = 0.027, respectively; Additional file 3E, F).