Other mutant genes (including FLT3-TKD, ETV6, IDH1, CBL, SETBP1, NPM1, TP53, EZH2, SF3B1, JAK) are found in fewer than 5% of ASXL1+ AML patients; PHF6 and ZRSR2 mutations are not seen in ASXL1+ AML patients. The gene discussed is NPM1; the disease is acute myeloid leukemia.