MGMT and neoplasm: There were no statistically significant differences between the IoUS and IoUS+IoMRI groups in terms of gender (Fisher Exact test, P = 0.188), pre-operative tumor volume (Mann-Whitney test, P = 0.15), involvement of eloquent structures (Fisher Exact Test; P = 0.74), MGMT status (Fisher Exact test, P = 1) or preoperative KPS score (Mann-Whitney test, P = 0.96).