PTEN and cancer: For example, 6q15 deletion was found in 25% of 173 HER2-amplified cancers but only in 17% of 748 cancers with normal HER2 copy-number status (p = 0.0159), as well as in 26% of 185 PTEN deleted cancers but only in 17% of 795 cancers with normal PTEN status (p = 0.0030).