After adjusting for potential confounding factors, multivariate Cox regression analysis showed that PCID2 overexpression was an independent predictor of recurrence in CRC patients (Cohort I: RR 1.140, 95% CI, 1.035–1.255; P = 0.008; Cohort II: RR 2.095, 95% CI, 1.089–4.031; P = 0.013) (Table 1). The gene discussed is PCID2; the disease is colorectal carcinoma.