The recurrently aberrant regions included genes implicated in the pathogenesis of NSCLC with known oncogenes such as MDM4 (1q), RIT1 (1q), DROSHA (5p), PIK3CA (3q), EGFR (7p), and NKX2–1 (14q), and tumor suppressor genes such as TP53 (17p). The gene discussed is TP53; the disease is non-small cell lung carcinoma.