After multivariate analysis, independent predictive factors associated to nodal pCR were axillary cCR evaluated on imaging after NAC (OR 2.95, 95%CI 2.36–3.68, p < 0.0001), ER-/HER2+ (OR 3.34, 95%CI 2.02–5.52, p < 0.0001) or ER+/HER2+ (OR 2.40, 95%CI 1.58–3.65, p < 0.0001) or ER-/HER2- (OR 1.94, 95%CI 1.34–2.81, p = 0.0004) biomolecular subtypes, breast cCR (OR 2.63, 95%CI 2.06–3.37, p < 0.0001), Ki67 > 14% (OR 1.76, 95%CI 1.24–2.51, p = 0.001), and histological tumor type “Others” (OR 2.06, 95%CI 1.22–3.47, p = 0.007), as showed in Table 2. Here, ERBB2 is linked to neoplasm.