Patients with severe or critical COVID-19 had lower lymphocyte count (1100 vs 1400 cells/mL; p<0.001), higher C-reactive protein (CRP) (27.5 mg/L vs. 6 p<0.001), D-dimer (0.9 vs. 0.5 μg/ml; p<0.001) and ferritin levels (780 vs. 344 ng/mL; p<0.001), respectively. The gene discussed is CRP; the disease is COVID-19.