In 2017, the International Neuroblastoma Response Criteria Bone Marrow Working Group recommended the collection of both bilateral BM biopsies and aspirates and their analysis with immunohistochemistry for GD2 and RTqPCR for tyrosine hydroxylase and paired-like homeobox 2B (PHOX2B) (Burchill et al. 2017). The gene discussed is TH; the disease is neuroblastoma.