SPP1 and cancer: FAB4 (fatty acid binding protein 4; FC, − 1.79) and SPP1 (secreted phosphoprotein 1, also called osteopontin; FC, − 1.67) have previously been shown to increase the metastatic potential of cancer cells, elevate angiogenesis, promote epithelial-mesenchymal transition (EMT), and suppress T cell activation in cancers [8, 9], whereas little is known about the functions of LINC00520 and CCDC102B in cancer.