By analyzing the GSE30528 data from glomeruli of patients with DKD, differentially expressed genes enriched in the mTORC1 signaling pathway, including PRKCB, RPS6KA1, ATP6V1B1, MAP2K2, PIK3CD, TNFRSF1A, PRR5, DEPDC5, PRKAA2, WNT16, TELO2, STK11, FZD3, MAPK1, WNT7A, MAPK3, LRP5, SEH1L, WDR59, RRAGC, TSC1, SOS1, WNT5B, ULK2, RPS6KA2, EIF4E, LPIN1, PIK3CA, SGK1, EIF4B, FZD2, and IGF1, were identified (Figure 3A). The gene discussed is FZD3; the disease is diabetic kidney disease.