By analyzing the GSE30528 data from glomeruli of patients with DKD, differentially expressed genes enriched in the mTORC1 signaling pathway, including PRKCB, RPS6KA1, ATP6V1B1, MAP2K2, PIK3CD, TNFRSF1A, PRR5, DEPDC5, PRKAA2, WNT16, TELO2, STK11, FZD3, MAPK1, WNT7A, MAPK3, LRP5, SEH1L, WDR59, RRAGC, TSC1, SOS1, WNT5B, ULK2, RPS6KA2, EIF4E, LPIN1, PIK3CA, SGK1, EIF4B, FZD2, and IGF1, were identified (Figure 3A). Here, PRKAA2 is linked to diabetic kidney disease.