By analyzing the GSE30528 data from glomeruli of patients with DKD, differentially expressed genes enriched in the mTORC1 signaling pathway, including PRKCB, RPS6KA1, ATP6V1B1, MAP2K2, PIK3CD, TNFRSF1A, PRR5, DEPDC5, PRKAA2, WNT16, TELO2, STK11, FZD3, MAPK1, WNT7A, MAPK3, LRP5, SEH1L, WDR59, RRAGC, TSC1, SOS1, WNT5B, ULK2, RPS6KA2, EIF4E, LPIN1, PIK3CA, SGK1, EIF4B, FZD2, and IGF1, were identified (Figure 3A). This evidence concerns the gene LRP5 and diabetic kidney disease.