In both groups, the distributions of these proteins are uniquely skewed in each compartment; in plasma, GFAP abounds (fold increases of 31, 136 and 15 relative to NFL, Tau and UCHL1 respectively for mTBI group; fold increases of 10, 24 and 3 relative to NFL, Tau and UCHL1 respectively for controls) while GluR2+ EVs are dominated by UCHL1 (fold increases of 6, 15 and 17 compared to GFAP, NFL and Tau respectively for mTBI group; fold increases of 8, 16 and 22 relative to GFAP, NFL and Tau respectively for controls). This evidence concerns the gene GFAP and concussion.