SOAT1 and Cognitive impairment: In addition, resveratrol is able to protect the hippocampal neurons, decrease inflammation and oxidative stress, and improve cognitive impairments by regulating the Janus kinases, extracellular signal-regulated kinases, and signal transducers and activators of the transcription (JAK/ERK/STAT) signaling pathway in rats with cerebral ischemia-reperfusion injury [78].