Tumor-related lipids MAGe, LPAe, LPCe, LPEe, PI, PC, and PS were downregulated, and the changes in the shR-AGPS1 group were more significant than those in the shR-AGPS2 group, but HNRNPK rescue can reverse the above phenomenon (Figure 3(b)), indicating that HNRNPK plays an important role in the regulation of glioma cell phenotype by AGPS. Here, HNRNPK is linked to central nervous system cancer.