Our previous studies have shown that silencing AGPS expression level can reduce glioma cell proliferation, invasion, and downregulation of the above-mentioned ether ester content by the PI3K/Akt and mTOR signaling pathway, lncRNAs, and microRNAs, indicating that AGPS plays a vital role in maintaining the pathogenic characteristics of glioma cells. The gene discussed is AKT1; the disease is central nervous system cancer.