A number of venom-derived compounds have been investigated in pre-clinical trials (Pennington et al., 2018; Bordon et al., 2020) or are in more advanced stages of clinical trials such as chlorotoxin derivates for tumour painting in intraoperative visualization (Patil et al., 2019), and the ShK-186 analogue derived from the venom peptide ShK from sea anemone for the treatment of autoimmune diseases such as psoriatic arthritis and lupus (Pennington et al., 2015). Here, SHPK is linked to autoimmune disease.