CD274 and neoplasm: In the multivariable Cox regression analysis using the same cofactors as described above, tumor PD-L1 positivity by both quantification methods independently predicted a favorable PFS (HR=0.53, 95%-CI=0.32–0.86, p=0.011) and OS (HR=0.47, 95%-CI=0.27–0.82, p=0.008) of the respective patients; Table 2.