Curcumin-loaded superparamagnetic iron oxide nanoparticles functionalized with sodium dodecyl sulfate (SDS) and coated with chitosan (40–45 nm), were able to induce apoptosis (IC50 30 μg/mL) in HeLa (cervical cancer) cells by damaging the DNA and increasing caspase-3 [136]. This evidence concerns the gene CASP3 and cervical carcinoma.