MMP2 and familial dilated cardiomyopathy: As shown in Figure 4(c), the level of MMP2 showed an increasing trend in the DCM group compared to the control group, and no change was observed between the DCM group and the DCM + FTZ group, while the protein level of MMP9 significantly decreased in the hearts of diabetic mice but was reversed by FTZ treatment (Figure 4(c)).