GRIN2A and focal epilepsy: The duplication present in patient IGGAC01 partially overlapped GRIN2A. Truncating as well as missense, activating variants of GRIN2A have been associated with an idiopathic form of focal epilepsy, EEG continuous spike-and-wave during sleep (CSWS), and speech disorder (OMIM 245570) (Lemke et al., 2013) whose clinical aspects are present in our patient.