We therefore performed univariate Cox regression for cohesin subunits SMC1A, RAD21, STAG1 and STAG2, and found a similar inverse correlation with overall survival across two independent cohorts of 322 and 757 DLBCL patients, with the exception of STAG1 (Figure 6E). This evidence concerns the gene STAG1 and diffuse large B-cell lymphoma.