For SAT, the amount of DE mRNAs of obesity was 185 (50 for overweight, 54 for obesity, and 107 for obesity with MS), and only 3 mRNAs (JSRP1, MRS2 and STK40) were shared by all these 3 obesity components as shown in Venn diagram (Figure 3D). Here, MRS2 is linked to obesity due to melanocortin 4 receptor deficiency.