Notably, in a preclinical model, researchers have found that DCN participates in the remodeling process of myocardial infarction by inducing abnormal collagen fibrotic evolution, which further compromises scar tissue (Weis et al., 2005), or by enhancing cardiomyocyte survival after stimulated ischemia/reperfusion injury (Gaspar et al., 2020). The gene discussed is DCN; the disease is myocardial infarction.