Interestingly, OACM5.1 C esophageal cancer cells with elevated c-Myc expression by either BIO or pcDNA3-cMyc were preferentially more sensitive to induction of apoptosis by the CDK inhibitor flavopiridol compared to the parent OACM5.1C esophageal cancer cells with lower c-Myc expression (Figures 2A–D). Here, MYC is linked to esophageal cancer.