RACK1 and immune system toxicity: Since RACK1 plays a pivotal role in immune cell activation (Corsini et al., 1999; Corsini et al., 2005; Corsini et al., 2014a; Corsini et al., 2014b; Buoso et al., 2017b; Buoso et al., 2017c; Racchi et al., 2017), and a complex hormonal balance is involved in the control of its expression (Buoso et al., 2011; Buoso et al., 2017b; Buoso et al., 2017c; Racchi et al., 2017; Corsini et al., 2021), it could represent a useful tool for the screening of EDCs and their immunotoxicity (Buoso et al., 2017a; Racchi et al., 2017; Buoso et al., 2020b; Corsini et al., 2021).