Similarly, immunohistochemical analysis of 128 CRCs, including 38 cases without metastasis on presentation, 51 with liver metastasis, 35 with lung metastasis, and four with both liver and lung metastasis, elevated CDCP1 correlated significantly with tumor size, grade and stage, and decreased lung metastasis free survival [3]. This evidence concerns the gene CDCP1 and metastasis.