The tectorial membrane is complex and consists of various proteins, one of the main proteins being α-tectorin, encoded by TECTA. We detected a missense variant in TECTA (Arg371Gly) that associates with vertigo (rs612969-G, EAF = 44.1%, P = 4.9 × 10−11, OR = 1.06). This evidence concerns the gene TECTA and Vertigo.