However, in a meta-analysis combining age-related hearing impairment (ARHI) data from Iceland and the UK (Ncases = 121,934, Ncontrols = 591,699)17, rs612969-G in TECTA has a small effect on ARHI (P = 9.9 × 10−5, OR = 1.02). The gene discussed is TECTA; the disease is presbycusis.