Moreover, when comparing the expression of these in the COVID-19 group, it can be observed that the IgA was the least immunoglobin expressed, followed by the IgM; being the IgG the most expressed immunoglobulin, which may be attributed to that most of the samples were collected at day 9.24 after PCR diagnosis, and according to the aforementioned the IgM is detected 5 days post symptom onset. The gene discussed is CD40LG; the disease is COVID-19.