Serum sFlt-1 being the soluble form of Vascular Endothelial Growth Factor receptor (sVEGFR) which binds and antagonizes Vascular Endothelial Growth Factor (VEGF) and Placental Growth Factor (PlGF) signal10 and it has been demonstrated to promote endothelial dysfunction, notably during preeclampsia11. Here, PGF is linked to endothelial dysfunction.