On multivariable analysis controlling for age and HIV status and compared to serotype 10A, serotypes 22A (coef: 26,090.77, HDI: 2389.31, 48,894.44), 7F (coef: 23,255.71, HDI: 1374.87, 44,902.99) and 15B/C (coef: 17,050.5, HDI: 614.6, 33,345.73) were associated with higher levels of IL-8 in the CSF of meningitis patients (Fig. 1B, Bayesian R2 = 0.44, Supplementary Table S5). This evidence concerns the gene CXCL8 and meningitis.