Human ATP6AP2/PRR is known to be a Parkinsonism candidate gene and its mutations in humans, mice or flies can lead to cognitive impairment, neurodegeneration and epilepsy (Korvatska et al., 2013; Dubos et al., 2015; Ichihara and Yatabe, 2019). The gene discussed is ATP6AP2; the disease is Parkinsonism.