All in all, we demonstrated that FCRL1 rs2050568 T/T genotype, FCRL3 rs2317230 G/T - T/T genotype, and FCRL6 rs58240276 T/T genotype were associated with RA risk in Chinese Han people, when the stratified analysis by age and gender was performed. Here, FCRL1 is linked to rheumatoid arthritis.