In the eleven lung cancer-specific methylation markers (CDO1, GSHR, HOXA11, HOXB4-1, HOXB4-2, HOXB4-3, HOXB4-4, LHX9, MIR196A1, PTGER4-1, and PTGER4-2), 21 CpG sites (cg09076431, cg07852825, cg15987088, cg08516516, cg11036833, cg23180938, cg27071460, cg15760840, cg14458834, cg21546671, cg08089301, cg09194159, cg14345497, cg02422694, cg07015911, cg12806763, cg19081437, cg24114154, cg26327071, cg21460081, and cg01452847) were found in the TCGA database. The gene discussed is MIR196A1; the disease is lung cancer.