There were no significant differences of TLR1, TLR3, TLR4, TLR5, TLR6, TLR8, TLR9, or TLR10 mRNA relative level in CD8+ T cells among peripheral bloods of NCs, peripheral bloods of GC patients, and tumor-residency of GC patients (One-Way ANOVA or Kruskal–Wallis test, all P > 0.05, Fig. 1). This evidence concerns the gene TLR4 and neoplasm.