TLR2 and neoplasm: TLR2 activation promoted cytolytic activity of both peripheral (18.48 ± 4.86%, paired t test, P = 0.0002, Fig. 5a) and tumor-infiltrating CD8+ T cells (18.48 ± 3.73%, paired t test, P < 0.0001, Fig. 5a) from GC patients.