Previous work in T98G glioblastoma cells has shown that phosphorylation of Ser67, Ser71, and/or Ser76 in the βTRCP-binding region of PDCD4 is necessary for βTRCP binding and subsequent proteasome-mediated degradation of PDCD4 (Dorrello et al., 2006). Here, PDCD4 is linked to glioblastoma.