Among these genes, gene MPO (with column number 1,720), CST3 (with column number 1,823), ZYX (with column number 4,788), CTSD (with column number 2,062), CD79A/MB-1(with column number 2,583), LYZ (with column number 6,738) in Leukemia dataset are important biomarkers as these are selected by different filter methods mentioned in Fig. S4. The gene discussed is ZYX; the disease is leukemia.