Our previous studies showed that PARK6 (PINK1) can promote migration and proliferation of lung cancer cells by regulating autophagy (Lu et al., 2020), and PARK7 (DJ-1) is necessary for the transcription of HIF-1α and survival of colorectal cancer cells (Lin et al., 2018; Zheng et al., 2018). This evidence concerns the gene PINK1 and colorectal cancer.