Among them, eight immunity related pathways (“primary immunodeficiency,” “allograft rejection,” “Rheumatoid arthritis,” “Hematopoietic cell lineage,” “Fc epsilon RI signaling pathway,” “B cell receptor signaling pathway,” “Intestinal immune network for IgA production,” and “Staphylococcus aureus infection”) and 4 signaling related pathways (“Calcium signaling pathways,” “Phospholipase D signaling pathway,” “NF-kappa B signaling pathway,” and “Cytokine-cytokine receptor interaction”) were commonly detected after the HFD or EGCG treatment. This evidence concerns the gene CD79A and rheumatoid arthritis.