Wang et al. (2021) revealed that lncRNA XIST promoted pyroptosis through the XIST/miR-150-5p/c-Fos axis, and Wan et al. (2020) discovered that lncRNA-H19 significantly promoted NLRP3/6 inflammasome imbalance and induced pyroptosis of microgliocyte. Furthermore, Tan et al. (2021) found that LncRNA HOTTIP could inhibit pyroptosis of ovarian cancer cells by targeting the miR-148a-3p/AKT2 axis. Here, XIST is linked to ovarian carcinoma.