Hashimoto et al. found that miR-940 is highly expressed in EVs from highly osteotropic prostate cancer cells, and promotes osteoblastic/osteosclerotic bone lesions by targeting Rho GTPase Activating Protein 1 (ARHGAP1) and family with sequence similarity 134 member A (FAM134A) (90). Here, ARHGAP1 is linked to Familial prostate cancer.