As shown in Fig. 2A, tumor stage, KPNA2 expression, and cg17985418 methylation were shown to be independent prognostic factors for HCC OS and the risk model was as follows: \documentclass[12pt]{minimal}\usepackage{amsmath}\usepackage{wasysym}\usepackage{amsfonts}\usepackage{amssymb}\usepackage{amsbsy}\usepackage{upgreek}\usepackage{mathrsfs}\setlength{\oddsidemargin}{-69pt}\begin{document}}{}\begin{eqnarray*}\mathrm{Risk~ score} \left( OS \right) =0.40271\ast \mathrm{tumor~ stage}+5.49197\ast cg17985418+0.55453\ast \nonumber\\\displaystyle KPNA2\mathrm{expression}. This evidence concerns the gene KPNA2 and neoplasm.