For evaluation of the CNV and CpG associations with HCC DFS (Table S4), KPNA2 CNV (p = 0.002) and the methylation value of cg14898140 (p = 0.006) were shown to have unfavorable prognostic effects on HCC DFS independent of age, gender, and tumor stage while no significant correlation of other CpG sites was shown. Here, KPNA2 is linked to hepatocellular carcinoma.