As shown in Fig. S2, the mutations of TP53 (p < 0.01), DNAH10 (p < 0.01), TSC2 (p < 0.01), and RB1 (p < 0.01) were associated with KPNA2 upregulation while KPNA2 was more reduced in HCC samples with BAP1 mutations (p < 0.01) than in those without BAP1 mutations. This evidence concerns the gene RB1 and hepatocellular carcinoma.