The network is highly enriched for cytokine-cytokine receptor interaction (FDR = 6.5E−06), I-kappaB kinase/NF-kappaB signaling (FDR = 1.6E−06), necroptosis (FDR = 3.3E−03), viral infections, such as Human Papillomavirus (FDR = 5.7E−04) and Herpes virus (FDR = 3.5E−03), JAK-STAT and PI3K-AKT signaling pathways, Toll-like receptor signaling, and immune system Homo sapiens (FDR = 3.7E−03). This evidence concerns the gene AKT1 and viral infectious disease.