Finally, we screened four groups of ceRNA regulatory triplets present in metastatic melanoma patients, in which AC104024.1 and RP11-594N15.3 served as key endogenous sponges that upregulated the expression level of target genes CSF2RB, ZNF831, and PKIA by competitive adsorbing miR-364 and miR-3662, respectively. The gene discussed is CSF2RB; the disease is metastatic melanoma.