ALS-related genes include mutations in superoxide dismutase 1, fused in sarcoma (FUS), transactive response DNA-binding protein 43 (TDP-43), C9orf72, optineurin, sequestosome 1, ubiquilin 2, dynactin, MATR3, and valosin-containing protein (VCP) [2]. The gene discussed is SOD1; the disease is amyotrophic lateral sclerosis.