By comparing the images of immunohistochemical staining in HNSCC tissue and normal tissues of the head and neck, we found that 11 DE-FRGs (ASNS, AURKA, FTH1, SLC2A3, SLC7A5, CISD2, PRDX6, ATG5, BAP1, MAP1LC3A, and SOCS1) showed differences in proteins expression (Figures 13A–K). The gene discussed is AURKA; the disease is head and neck squamous cell carcinoma.