Consistent with the results obtained for other types of cancer (Xing et al., 2018; Zhao et al., 2018; Ruan and Zhao, 2019; Vidovic et al., 2020; Wang et al., 2020a, b), an exceptionally high Linc00284 expression was also observed in LC, suggesting that Linc00284 may be an important tumor-promoting factor. This evidence concerns the gene NRAD1 and laryngotracheoesophageal cleft.